Research Paper 02

Facial Appearance Improvements and Gene Expression Changes with Topical Formulation for DNA Damage Repair.

Professor Yohei Tanaka, MD

Paper Summary

This paper focuses on the potential of #6 The Night Crème to assist in DNA repair and enhancing skin firmness, hydration and luminosity.

In a 28- and 56-day in vivo study, #6 The Night Crème showed significant skin improvement: 100% reported better hydration and firmness, along with increased radiance, clarity, and reduced redness. 

In vitro, tests confirmed enhanced skin cell health and gene expression related to repair and rejuvenation. Notably, genes involved in retinol conversion, retinoid absorption, collagen synthesis, and skin barrier function showed substantial increases: up to 1738%, 574%, 398%, and 1064%, respectively.

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Paper Details

Title:

In Vivo Improvements in Facial Appearance and In Vitro Changes in Gene Expression Using a Topical Formulation Designed to Repair Environmentally Induced DNA Damage.

Participants:

22

Formulations of Focus:

#6 The Night Crème

Results:

In a 28- and 56-day in vivo study, #6 The Night Crème showed significant skin improvement: 100% reported better hydration and firmness, along with increased radiance, clarity, and reduced redness.

In vitro, tests confirmed enhanced skin cell health and gene expression related to repair and rejuvenation. Notably, genes involved in retinol conversion, retinoid absorption, collagen synthesis, and skin barrier function showed substantial increases: up to 1738%, 574%, 398%, and 1064%, respectively.

Explained by Founder and Direction of Research, Richard Parker